{"id":2547,"date":"2021-12-10T12:34:33","date_gmt":"2021-12-10T12:34:33","guid":{"rendered":"https:\/\/www.genesis-foundation.net\/blog\/?p=2547"},"modified":"2025-12-26T17:40:18","modified_gmt":"2025-12-26T17:40:18","slug":"multisystem-inflammatory-syndrome-in-children-mis-c-and-covid-19","status":"publish","type":"post","link":"https:\/\/www.genesis-foundation.net\/blog\/multisystem-inflammatory-syndrome-in-children-mis-c-and-covid-19\/","title":{"rendered":"Multisystem Inflammatory Syndrome in Children (MIS-C) and COVID-19"},"content":{"rendered":"<p class=\"img-float-left max-width-desktop-300\" style=\"text-align: center;\"><img decoding=\"async\" class=\"img-responsive alignleft\" style=\"max-width: 100%;\" src=\"https:\/\/www.genesis-foundation.net\/blog\/wp-content\/uploads\/2021\/12\/MIS-C.jpg\" alt=\"Heart\" \/><\/p>\n<p style=\"text-align: justify;\">Until now it has been seen that most children who become infected with the COVID-19 virus have only a mild illness. But in children who go on to develop Multisystem Inflammatory Syndrome or more commonly known as MIS-C, some organs and tissues \u2014 such as the heart, lungs, blood vessels, kidneys, digestive system, brain, skin or eyes \u2014 become severely inflamed. First identified in April 2020, it may or may not have a definite history of COVID-19 in the past. Research is still ongoing on the role it plays in treatment for Congenital Heart Defects.<\/p>\n<p><strong>Symptoms of MIS-C<\/strong><\/p>\n<p style=\"text-align: justify;\">Signs and symptoms of MIS-C depend on which areas of the body are affected. Some common ones are below, though not all children have the same symptoms:<\/p>\n<ul style=\"margin-left: 14px;\">\n<li>Fever that lasts 24 hours or longer<\/li>\n<li>Gastrointestinal symptoms like vomiting, diarrhoea, pain in the stomach<\/li>\n<li>Skin rash<\/li>\n<li>Feeling unusually tired<\/li>\n<li>Fast heartbeat<\/li>\n<li>Rapid breathing<\/li>\n<li>Red eyes<\/li>\n<li>Redness or swelling of the lips and tongue<\/li>\n<li>Redness or swelling of the hands or feet<\/li>\n<li>Headache, dizziness or light-headedness<\/li>\n<li>Enlarged lymph nodes<\/li>\n<\/ul>\n<p style=\"text-align: justify;\">There are some emergency warning signs of MIS-C too, which should not be taken lightly by parents or caretakers:<\/p>\n<ul style=\"margin-left: 14px;\">\n<li>Severe stomach pain<\/li>\n<li>Difficulty in breathing<\/li>\n<li>Pale, grey or blue-colored skin, lips, or nail beds \u2014 depending on skin tone<\/li>\n<li>New confusion<\/li>\n<li>Inability to wake up or stay awake<\/li>\n<li>Inflammation of the heart<\/li>\n<li>Kidney injury<\/li>\n<\/ul>\n<p style=\"text-align: justify;\">One of the most dangerous symptoms of MIS-C is swelling of the coronary arteries, which is why prompt diagnosis and treatment of the illness is vital, similar to steps taken during congenital heart defect treatment.<\/p>\n<p><strong>Steps for Prevention<br \/>\n<\/strong><\/p>\n<ul style=\"margin-left: 14px;\">\n<li style=\"text-align: justify;\"><strong>Keep hands clean<\/strong><br \/>\nMake sure you, as well as your child, washes hands often with soap and water for at least 20 seconds. In case that isn\u2019t available, use a hand sanitizer that contains at least 60% alcohol.<\/li>\n<li style=\"text-align: justify;\"><strong>Avoid people who are sick<\/strong><br \/>\nIn particular, avoid people who are coughing, sneezing or showing other signs that indicate their illness might be contagious.<\/li>\n<li style=\"text-align: justify;\"><strong>Practice social distancing<\/strong><br \/>\nThis means that you and your child should stay at least 6 feet (2 meters) from other people when outside of your home.<\/li>\n<li style=\"text-align: justify;\"><strong>Wear face masks in public<\/strong><br \/>\nWhen in indoor public places or outdoors where there is a high risk of Covid-19 transmission, such as a crowded event or a large gathering, both you and your child \u2014 if he or she is at least 2 years old \u2014 should wear face masks that cover the nose and mouth. Further mask guidance differs depending on whether you are fully vaccinated or unvaccinated.<\/li>\n<li style=\"text-align: justify;\"><strong>Avoid touching your face<\/strong><br \/>\nNot touching your nose, eyes and mouth encourages the child also to follow the parents\u2019 lead and avoid touching his or her face.<\/li>\n<li style=\"text-align: justify;\"><strong>Covering the mouth while sneezing<\/strong><br \/>\nOne should use a tissue when sneezing or coughing to avoid spreading germs.<\/li>\n<li style=\"text-align: justify;\"><strong>Cleanliness and disinfection<\/strong><br \/>\nHighly-touched surfaces should be cleaned every day. This includes areas such as doorknobs, light switches, remotes, handles, countertops, tables, chairs, desks, keyboards, faucets, sinks and toilets etc.<\/li>\n<li style=\"text-align: justify;\"><strong>Wash clothing and other items<\/strong><br \/>\nMaintaining hygiene, it\u2019s important that children\u2019s clothes and other items like plush toys are washed regularly.<\/li>\n<\/ul>\n<p><strong>Detection of MIS-C<\/strong><\/p>\n<p style=\"text-align: justify;\">In addition to antibody testing and a clinical assessment, doctors may order some of these tests to look for inflammation and other signs of MIS-C:<\/p>\n<ul style=\"margin-left: 14px;\">\n<li style=\"text-align: justify;\">Lab tests, such as blood and urine tests, including tests that look for an abnormal level of inflammatory markers in the blood<\/li>\n<li style=\"text-align: justify;\">Imaging tests, such as a chest X-ray, an echocardiogram, an abdominal ultrasound or a CT scan<\/li>\n<li>Other tests, depending on signs and symptoms<\/li>\n<\/ul>\n<p><strong>Treatment of MIS-C<\/strong><\/p>\n<p style=\"text-align: justify;\">The treatment is best taken under the care of the pediatrician, who may also seek the support of a paediatric cardiologist who specialises in <a href=\"https:\/\/www.genesis-foundation.net\/about-congenital-heart-defects\" target=\"_blank\" rel=\"noopener noreferrer\">congenital heart defect treatment<\/a>. Echocardiography during the episode, and during follow up is important supportive investigation to tailor the therapy to be provided to the child.<\/p>\n<p>Supportive care may include:<\/p>\n<ul style=\"margin-left: 14px;\">\n<li style=\"text-align: justify;\">Fluids, if levels are too low (dehydration)<\/li>\n<li style=\"text-align: justify;\">Oxygen to help with breathing<\/li>\n<li style=\"text-align: justify;\">Blood pressure medications to normalize low blood pressure related to shock or to help with heart function<\/li>\n<li style=\"text-align: justify;\">A breathing machine (ventilator)<\/li>\n<li style=\"text-align: justify;\">Medications that reduce the risk of blood clots, such as aspirin or heparin<\/li>\n<li style=\"text-align: justify;\">In very rare cases, extracorporeal membrane oxygenation (ECMO) using a machine that does the work of the heart and lungs<\/li>\n<\/ul>\n<p style=\"text-align: justify;\">Until now, there is no evidence that suggests that MIS-C is contagious. It is important that a regular follow-up with a pediatric cardiologist who specializes in <a href=\"https:\/\/www.genesis-foundation.net\/about-congenital-heart-defects\" target=\"_blank\" rel=\"noopener noreferrer\">treatment for Congenital Heart Defects<\/a> is sought to tailor therapy in the interest of the child\u2019s wellbeing.<\/p>\n<p><em>Dr Neeraj Awasthy is the Principal Consultant &amp; In-charge of the Paediatric Cardiology department at our partner hospital \u2013 Max Hospital, Saket. With over 18 years of experience, he has corrected various types of Congenital Heart Defects.<\/em><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Until now it has been seen that most children who become infected with the COVID-19 virus have only a mild illness. But in children who go on to develop Multisystem Inflammatory Syndrome or more commonly known as MIS-C, some organs and tissues \u2014 such as the heart, lungs, blood vessels, kidneys, digestive system, brain, skin [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":2553,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[1],"tags":[],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v20.9 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Multisystem Inflammatory Syndrome in Children (MIS-C) and COVID-19 - Blog<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.genesis-foundation.net\/blog\/multisystem-inflammatory-syndrome-in-children-mis-c-and-covid-19\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Multisystem Inflammatory Syndrome in Children (MIS-C) and COVID-19 - Blog\" \/>\n<meta property=\"og:description\" content=\"Until now it has been seen that most children who become infected with the COVID-19 virus have only a mild illness. 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